Lorne Cancer Conference 2019

Professor William Weiss

Dr. Weiss co-leads that Pediatric Malignancies Program within UCSF's Helen Diller Family Comprehensive Cancer Center, is deputy editor of Cancer Research, and associate editor of Cell Stress, Molecular and Cellular Biology, Neuro-Oncology, and Scientific Reports.


The Weiss lab has developed genetically engineered and human iPSC-based mouse models for glioma, medulloblastoma and neuroblastoma; establishing these as platforms for biology, genetics, and developmental therapeutics, in parallel with analyses of primary human tumors. The lab has a long-standing interest in developmental therapeutics, focused on EGFR, PI3K, and mTOR biology; chemical genetic approaches to kinase function, and on developing inhibitors of kinases that stabilize MYC family proteins, as a MYC-directed therapy.